Nanomedicine: current status and future prospects.
نویسندگان
چکیده
Applications of nanotechnology for treatment, diagnosis, monitoring, and control of biological systems has recently been referred to as "nanomedicine" by the National Institutes of Health. Research into the rational delivery and targeting of pharmaceutical, therapeutic, and diagnostic agents is at the forefront of projects in nanomedicine. These involve the identification of precise targets (cells and receptors) related to specific clinical conditions and choice of the appropriate nanocarriers to achieve the required responses while minimizing the side effects. Mononuclear phagocytes, dendritic cells, endothelial cells, and cancers (tumor cells, as well as tumor neovasculature) are key targets. Today, nanotechnology and nanoscience approaches to particle design and formulation are beginning to expand the market for many drugs and are forming the basis for a highly profitable niche within the industry, but some predicted benefits are hyped. This article will highlight rational approaches in design and surface engineering of nanoscale vehicles and entities for site-specific drug delivery and medical imaging after parenteral administration. Potential pitfalls or side effects associated with nanoparticles are also discussed.
منابع مشابه
Small Hydro-Power Plants in Kenya: A Review of Status, Challenges and Future Prospects
Small Hydro-power Plants (SHP) are an important source of electricity in many countries. However, little is known about SHP in Kenya. This paper reviews the status, challenges in implementation of SHP and prospects for future development of SHP in Kenya. The paper shows that SHP has not yet fully utilized the available hydro-power potential. The challenges associated with SHP development should...
متن کاملReverse Electrodialysis for Salinity Gradient Power Generation: Challenges and Future Perspectives
Salinity gradient energy, which is also known as Blue energy, is a renewable energy form that can be extracted from the mixing of two solutions with different salinities. About 80% of the current global electricity demand could potentially be covered by this energy source. Among several energy extraction technologie...
متن کاملScenario and future prospects of microRNAs in gastric cancer: A review
Carcinoma of the stomach is one of the major prevalent and principal causes of cancer-related deaths worldwide. Current advancement in technology has improved the understanding of the pathogenesis and pathology of gastric cancers (GC). But, high mortality rates, unfavorable prognosis and lack of clinical predictive biomarkers provide an impetus to investigate novel early diagnostic/prognostic m...
متن کاملThe current status of Pythium species in Iran: challenges in taxonomy
Pythium species are cosmopolitan, fungus-like oomycotes which may cause diseases in plants, animals and even human beings. Some of the species, however, are saprophytes and also well-proven biological control agents of plant pathogenic fungi. Since 1968, when the first Pythium species was reported from Iran, ca 44 species, two varieties, and five groups of this genus have been reported from dif...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology
دوره 19 3 شماره
صفحات -
تاریخ انتشار 2005